Status:
COMPLETED
Impact of the Source and Food Matrices on the Bioavailability of Peptan® (Collagen Peptides) in Healthy Subjects
Lead Sponsor:
Rousselot BVBA
Collaborating Sponsors:
BioTeSys GmbH
Conditions:
Bioavailability
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
The aim of this study is the comparison of the oral bioavailability of hydroxyproline, a key marker for collagen peptide intake, after ingestion of collagen peptides from different sources, sizes and ...
Detailed Description
The absorption (blood) of collagen peptides from bovine, fish and porcine source in different sizes and administered together with foods of different polyphenol content will be assessed. Pharmacokinet...
Eligibility Criteria
Inclusion
- Main
- Subject is able and willing to sign the Informed Consent Form prior to screening evaluations
- Sex: female and male (50 % of each gender)
- Age: 18-50 years
- BMI ≥19 and ≤28 kg/m²
- Nonsmoker
- Main
Exclusion
- Relevant history or presence of any severe medical disorder, potentially interfering with this study (e.g. mal absorption, chronic gastro-intestinal diseases, heavy depression, diabetes, acute cancers within last 3 years except basal cell carcinoma of the skin, etc.)
- Significant changes in lifestyle or medication (within last 3 mo.) or surgical intervention or surgical procedure such as bariatric surgery
- Application of corticoids (intravenously, orally or intraarticularly) and other immune-suppressing drug (within last 2 weeks)
- Blood donation within 1 month prior to study start or during study
- Regular intake of drugs or supplements possibly interfering with this study (Glucosamine, chondroitin sulfate, hyaluronic acid, omega-3, folic acid, curcumin/turmeric, Boswellia serrata, collagen, Vitamin D) within 2 weeks prior to study start or during study
- Intake of anticoagulants like Heparin, Marcumar etc.
- Coffee consumption \>3 cups / day
- History of hypersensitivity to fish
Key Trial Info
Start Date :
September 20 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 25 2019
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT04097808
Start Date
September 20 2019
End Date
October 25 2019
Last Update
April 30 2020
Active Locations (1)
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1
BioTeSys GmbH
Esslingen am Neckar, Germany, 73728