Status:
RECRUITING
MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics
Lead Sponsor:
Mayo Clinic
Conditions:
Hydrocephalus
Alzheimer Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The Researchers are trying to test a MR imaging method for detection of Cerebral Spinal Fluid (CSF) flow in the brain to help diagnosis and better understand diseases that affect brain function.
Detailed Description
The purpose of this research is to figure out if MR imaging can detect movement of CSF (fluid around the brain) to help better diagnosis and understand the cause of diseases that affect brain function...
Eligibility Criteria
Inclusion
- A healthy control will be defined as an otherwise healthy person who does not have a medical condition that affects brain function or have problems with concentration, memory, balance, or coordination.
- Patients who have a suspected diagnosis of altered CSF dynamics including but not limited to normal pressure hydrocephalus will be referred to Dr. Cogswell by their care team to be included in the study. Conditions of altered CSF dynamics include obstructive and non-obstructive hydrocephalus and may be associated with headaches and/or decreased cognitive function.
- Similarly, patients with impaired cognitive function including but not limited to Alzheimer's disease will be referred to Dr. Cogswell by their care team to be included in the study.
Exclusion
- Subjects with non-MRI compatible devices
- required sedation
- women who may be pregnant will be excluded.
- The first 10 subjects with normal pressure hydrocephalus will not have previously been shunted.
Key Trial Info
Start Date :
October 31 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2027
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04099823
Start Date
October 31 2019
End Date
January 1 2027
Last Update
January 6 2026
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55905