Status:
UNKNOWN
Biomarkers of Common Eye Diseases
Lead Sponsor:
Sun Yat-sen University
Conditions:
Uveitis
Diabetic Retinopathy
Eligibility:
All Genders
18+ years
Brief Summary
To identify biomarkers of common eye diseases based on single-cell sequencing technologies using PBMC samples. These diseases include uveitis, diabetic retinopathy, age-related macular degeneration an...
Detailed Description
The pathogenesis of common eye diseases such as uveitis (including Behcet's disease (BD) and Vogt-Koyanagi-Harada disease (VKH)), diabetic retinopathy (DR), age-related macular degeneration (AMD) and ...
Eligibility Criteria
Inclusion
- Inclusion Criteria for patients:
- Age over 18 (including 18 years old);
- Clinically diagnosed as diabetic retinopathy (DR), uveitis (VKH or BD) , age-related macular degeneration (AMD) , or polypoid choroidal vasculopathy (PCV)
- Exclusion Criteria for patients with retinal diseases:
- Have received more than 2 intravitreal injections of anti-VEGF drugs because of retinal or choroidal neovascularization and macular edema;
- Patients with stable condition after having undergone panretinal laser photocoagulation and pars plana vitrectomy (PPV);
- There are other serious systemic diseases of the body, such as history of chronic kidney disease requiring dialysis or a kidney transplant, unstable blood pressure, cardiovascular disease, tumors, etc;
- Patients who are pregnant or nursing
Exclusion
Key Trial Info
Start Date :
September 26 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2021
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT04101604
Start Date
September 26 2019
End Date
October 1 2021
Last Update
September 27 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Zhognshan Ophthalmic Center, Sun Yat-sen University
Guangzhou, Guangdong, China, 510000