Status:

COMPLETED

Prolonged Exposure Therapy for PTSD and Opioid Use Disorder

Lead Sponsor:

University of Vermont

Collaborating Sponsors:

National Institute of General Medical Sciences (NIGMS)

Conditions:

Post Traumatic Stress Disorder

Opioid-use Disorder

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Among patients with opioid use disorder (OUD), 90% report lifetime trauma exposure and 33% meet criteria for posttraumatic stress disorder (PTSD). The co-occurrence of OUD and PTSD is associated with ...

Detailed Description

Among patients with opioid use disorder (OUD), 90% report lifetime trauma exposure and 33% meet criteria for posttraumatic stress disorder (PTSD). The co-occurrence of OUD and PTSD is associated with ...

Eligibility Criteria

Inclusion

  • \>18 years old
  • currently maintained on a stable methadone or buprenorphine dose for \>1 month prior to the study
  • endorse \>1 lifetime traumatic event
  • meet current DSM-V posttraumatic stress disorder criteria

Exclusion

  • Presence of an acute psychotic disorder, bipolar disorder with an active manic episode
  • imminent risk for suicide
  • a medical condition that may interfere with consent or participation
  • illiteracy in English

Key Trial Info

Start Date :

April 6 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 31 2023

Estimated Enrollment :

52 Patients enrolled

Trial Details

Trial ID

NCT04104022

Start Date

April 6 2021

End Date

July 31 2023

Last Update

January 9 2025

Active Locations (1)

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1

University of Vemont

Burlington, Vermont, United States, 05401