Status:
TERMINATED
Impact of an Optimised Monitored Anesthesia on the Patients' Recovery After Cytoreduction Surgery Plus HIPEC
Lead Sponsor:
Ciusss de L'Est de l'Île de Montréal
Conditions:
Hyperthermia
Colorectal Neoplasms
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The objective of our PILOT study is to evaluate the impact of a controlled (monitored) randomized anesthesia during cytoreductive surgery with HIPEC to oxaliplatin in order to treat adenocarcinomas of...
Detailed Description
Title: Evaluation of the combined intraoperative monitoring of depth of analgesia (NOL), depth of anesthesia (BIS) and continuous hemodynamic data (Flotrac EV1000 system) on the patients' recovery aft...
Eligibility Criteria
Inclusion
- ASA status I, II or III
- Patients older than 18 years
- HIPEC for bowel surgery with oxaliplatin + dextrose 5% for a duration of 30 min
- Duration and type of surgery requiring an epidural analgesia via an epidural catheter placed and tunnelled prior the general anesthesia induction and an arterial line placed after induction of general anesthesia.
Exclusion
- Any allergy to one drug used in our anesthesia or HIPEC protocol
- Any contra-indication or patient's refusal for epidural placement
- Chronic arrhythmic cardiac conditions
- Chronic pain with use of opioids more than 3 times per week for 4 weeks
- Bowel occlusion
- Physical/mental incapacities
- Unexpected difficult airway requesting excessive, possibly painful airway manipulations.
- Epidural failure
Key Trial Info
Start Date :
May 8 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 30 2020
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT04104334
Start Date
May 8 2019
End Date
November 30 2020
Last Update
October 8 2021
Active Locations (1)
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1
Hopital Maisonneuve Rosemont, CIUSSS de l'Est de l'Ile de Montréal
Montreal East, Quebec, Canada, H1T 2M4