Status:
TERMINATED
Olfaction and Inflammation in Chronic Rhinosinusitis With Nasal Polyps
Lead Sponsor:
Centre Hospitalier Universitaire de Saint Etienne
Conditions:
Nasal Polyps
Chronic Rhinosinusitis With Nasal Polyps
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Impaired olfaction is one of the major complaints of patients with nasosinus polyposis, with nasal obstruction. In case of failure of medical treatment for patients with polyposis nasosinusal, they ma...
Eligibility Criteria
Inclusion
- Inclusion Criteria for patients :
- Patients with nasosinus polyposis requiring nasosinus surgery
- Patient affiliated or entitled to a social security
- signed consent
- Inclusion Criteria for control group :
- Patients with an indication for septoplasty
- Patient affiliated or entitled to a social security
- signed consent
- Exclusion Criteria for patients :
- Patients with nasosinus polyposis secondary to another disease
- Patients with hyposmia or anosmia prior to naso-sinus polyposis
- Patients with diagnosed neurodegenerative disease
- Patients who are mentally or physically unable to perform olfactory tests
- Patients on anti-TNF-alpha therapy, long-term oral corticosteroid therapy, or other immunomodulatory therapy.
- Exclusion Criteria for control group :
- Patients with nasosinus polyposis
- Patients with chronic rhino-sinusitis
- Patients with hyposmia or anosmia
- Patients with diagnosed neurodegenerative disease
- Patients who are mentally or physically unable to perform olfactory tests
- Patients on anti-TNF-alpha therapy, long-term oral corticosteroid therapy, or other immunomodulatory therapy.
Exclusion
Key Trial Info
Start Date :
February 5 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 29 2021
Estimated Enrollment :
3 Patients enrolled
Trial Details
Trial ID
NCT04104594
Start Date
February 5 2020
End Date
July 29 2021
Last Update
October 25 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Chu Saint-Etienne
Saint-Etienne, France