Status:

UNKNOWN

HLA Analysis in Autoimmune Encephalitis and Related Disorders

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Autoimmune Encephalitis

Imbic Encephalitis

Eligibility:

All Genders

18+ years

Brief Summary

Autoimmune encephalitis (AE) are characterized by subacute onset of memory deficits, altered mental status or psychiatric symptoms, frequently associated with seizures, inflammatory cerebrospinal flui...

Eligibility Criteria

Inclusion

  • Presence of anti-LGI1, anti-CASPR2 or anti-GAD antibodies in serum or cerebrospinal fluid;
  • Clinical picture compatible with the detected antibody (limbic encephalitis in anti-LGI1; limbic encephalitis, neuromyotonia or Morvan's syndrome in anti-CASPR2; limbic encephalitis, cerebellar ataxia or stiff-person syndrome in anti-GAD

Exclusion

  • \- Absence of complete clinicobiological data.

Key Trial Info

Start Date :

October 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2020

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT04106596

Start Date

October 1 2019

End Date

October 1 2020

Last Update

September 27 2019

Active Locations (1)

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Centre de référence des syndromes neurologiques paranéoplasiques et encéphalites auto-immunes

Lyon, France