Status:

COMPLETED

Predicting Endometrial Receptivity for Optimal Reproductive Management

Lead Sponsor:

Stanford University

Collaborating Sponsors:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Conditions:

Infertility, Female

Endometriosis

Eligibility:

FEMALE

18-42 years

Brief Summary

The purpose of this study is to understand why some women are infertile (unable to conceive a child). The investigators hope to learn if an endometrial biopsy after egg retrieval is feasible for detec...

Detailed Description

The investigators will recruit 100 women who are undergoing IVF with egg retrieval and delayed embryo transfer to consent to endometrial biopsy 1 week after egg retrieval. Currently most women in the ...

Eligibility Criteria

Inclusion

  • Age - 18 to 42
  • AMH ≥ 1
  • Planning to undergo IVF with delayed embryo transfer
  • Must have blastocyst(s) by day 6 that were biopsied for PGT-A
  • BMI 18-35

Exclusion

  • Uterine fibroids \> 4 cm in size
  • Polycystic ovary syndrome (PCOS) according with the Rotterdam criteria.
  • Ovarian failure and subjects receiving donor oocytes/embryos
  • Anti-cardiolipid and/or lupus anti-coagulant abnormalities by history
  • Diabetes mellitus (Type I or Type II)
  • Untreated hypothyroidism
  • Hyperprolactinemia
  • Uncorrected uterine anomaly

Key Trial Info

Start Date :

July 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 30 2024

Estimated Enrollment :

76 Patients enrolled

Trial Details

Trial ID

NCT04107129

Start Date

July 1 2020

End Date

July 30 2024

Last Update

August 14 2024

Active Locations (1)

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Stanford Fertility and Reproductive Health

Sunnyvale, California, United States, 94087