Status:
TERMINATED
Photoacoustic Imaging for Measuring Tumors and Normal Tissue in Patients With Head and Neck Cancer
Lead Sponsor:
Roswell Park Cancer Institute
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Head and Neck Carcinoma
Head and Neck Lymph Node
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This trial studies how well photoacoustic imaging works in measuring tumors and normal tissue in patients with head and neck cancer. Photoacoustic imaging (PAI) is a low-risk imaging method that provi...
Detailed Description
PRIMARY OBJECTIVE: I. Define the feasibility of the current photoacoustic imaging (PAI) technology in head and neck (H\&N) cancer patients. SECONDARY OBJECTIVE: I. Define the utility of the current...
Eligibility Criteria
Inclusion
- No restriction on race or ethnic background
- Subject must understand the investigational nature of the study and sign an independent ethics committee/institutional review board approved written informed consent prior to receiving any study related procedure
- FOR CANCER PATIENTS IN THE H\&N RADIATION GROUP (PART I):
- Biopsy-confirmed diagnosis of head and neck squamous cell carcinoma (HNSCC) getting chemoradiation therapy
- Presence of neck nodes or laryngeal tumor superficial enough (within 2-3 cm of skin surface) to allow imaging by photoacoustic ultrasound (PA-US)
- FOR ALTENS PATIENTS (PART II):
- History of prior radiation therapy with xerostomia requiring ALTENS
Exclusion
- Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
- Unwilling or unable to follow protocol requirements or provide consent
- Any condition which in the Investigator?s opinion deems the subject an unsuitable candidate to undergo imaging procedure
Key Trial Info
Start Date :
September 6 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 29 2022
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT04110249
Start Date
September 6 2019
End Date
December 29 2022
Last Update
April 10 2023
Active Locations (1)
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1
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263