Status:
COMPLETED
Left Bundle Branch Pacing Versus Biventricular Pacing for Cardiac Resynchronization Therapy
Lead Sponsor:
The First Affiliated Hospital with Nanjing Medical University
Collaborating Sponsors:
Fu Wai Hospital, Beijing, China
Conditions:
Chronic Heart Failure
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The present study will recruit 40 symptomatic heart failure patients with left ventricular ejection fraction (LVEF) below 35% and complete left bundle branch block(QRSd≥130 ms). Each patient was rando...
Detailed Description
The traditional biventricular pacing (BivP) is an established treatment to corrected the cardiac dyssynchrony in heart failure patients with left bundle branch block(LBBB). It has been proved that Biv...
Eligibility Criteria
Inclusion
- LVEF≤35% as assessed by echocardiography and NYHA class II-IV despite optimal medical therapy for at lest 3 months；
- Sinus rhythm, complete left bundle branch block (QRS duration ≥130ms)；
- Between the ages of 18 and 80；
- With informed consent signed.
Exclusion
- After mechanical tricuspid valve replacement；
- Unstable angina, acute MI, CABG or PCI within the past 3 months;
- Persistent atrial fibrillation without atrioventricular block, the expected percentage of ventricular pacing below 95%;
- Enrollment in any other study；
- A life expectancy of less than 12 months；
- Pregnant or with child-bearing potential;
- History of heart transplantation.
Key Trial Info
Start Date :
November 14 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 29 2021
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04110431
Start Date
November 14 2019
End Date
June 29 2021
Last Update
March 18 2022
Active Locations (2)
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1
The First Affiliated Hospital with Nanjing Medical University
Nanjing, Jiangsu, China, 210029
2
Fu Wai Hospital, Beijing, China
Beijing, China