Status:

UNKNOWN

Comparative Effect of Hypotensive Anaesthesia on Event Related Potentials, Quantitative Electroencephalograghy

Lead Sponsor:

Beni-Suef University

Conditions:

Effect of Drugs

Eligibility:

All Genders

20-50 years

Phase:

EARLY_PHASE1

Brief Summary

AIM OF THE WORK The aim of this work was to compare the effect of hypotensive anaesthesia using Nitroglycerine versus phentolamine on Event related potentials, quantitative Electroencephalograghy and ...

Detailed Description

METHODS: Study design and population: This is a pilot prospective randomized clinical trial that will be carried out on 60 patients candidate for septoplasty subjected to general hypotensive anaesthe...

Eligibility Criteria

Inclusion

  • Patients who are candidate for septoplasty
  • Patients from both sexes, aged between 20-50 years

Exclusion

  • Patients who develop intraoperative shock or major bleeding
  • Patients with ischemic heart diseases, heart block, congestive heart failure, valvular heart diseases, or uncontrolled hypertension
  • Patients with a history of central neurological system disorder
  • Patients with concomitant medical or metabolic illness known to affect cognition
  • Pregnant females
  • Allergy to any of the anaesthetic or hypotensive drugs used in the study

Key Trial Info

Start Date :

October 15 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2020

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04110808

Start Date

October 15 2019

End Date

February 1 2020

Last Update

October 1 2019

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