Status:
WITHDRAWN
Improving Outcomes After Time Sensitive Prehospital Interventions: Rescu Epistry
Lead Sponsor:
Unity Health Toronto
Collaborating Sponsors:
Canadian Institutes of Health Research (CIHR)
Heart and Stroke Foundation of Canada
Conditions:
Cardiac Arrest
Sepsis
Eligibility:
All Genders
Brief Summary
Rescu Epistry includes data points pertaining to prehospital and in-hospital clinical treatments and responses to therapy, survival to discharge and functional outcome data for all cases.
Detailed Description
The prehospital component of health care begins with a call to 911 and ends on arrival to the Emergency Department (ED). In Ontario, prehospital care is provided by a system which includes 22 dispatch...
Eligibility Criteria
Inclusion
- Cardiac Arrest Eligibility
- Individuals of all ages who experience cardiac arrest outside the hospital, with evaluation by organized EMS personnel and:
- Attempts at external defibrillation (by lay responders or emergency personnel), or chest compressions by organized EMS personnel (treated cohort)
- Were pulseless but did not receive attempts to defibrillate or CPR by EMS personnel (untreated cohort - obviously dead by legislative definition)
- Traumatic Injury Eligibility
- Individuals of all ages who experience a traumatic injury outside the hospital, with evaluation by organized EMS personnel and:
- Systolic blood pressure ≤ 90 mmHg or
- Glasgow Coma Scale score ≤12 or
- Respiratory rate \<10 or \>29 breaths per minute or
- Field intubation/advanced airway procedure
- Stroke Eligibility
- individuals of all ages who experience stroke outside the hospital, with evaluation by organized EMS personnel and new onset of signs and symptoms suggestive of an acute stroke
- Unilateral arm/leg weakness or drift or
- Slurred speech or inappropriate words or mute or
- Unilateral facial droop
- Sepsis Eligibility
- Potentially Septic: Individuals of all ages who present with
- Presence of Fever: Temperature \>38°C (tympanic membrane)
- Paramedic suspects possible infection: i.e. suspected pneumonia, urinary tract infection, abdominal pain or distension, meningitis, cellulitis, septic arthritis, infected wound (minimal data set )
- Severe Sepsis: Individuals of all ages who also present with:
- Presence of Fever: Temperature \>38°C (tympanic membrane)
- Paramedic suspects possible infection: e.g. suspected pneumonia, urinary tract infection, abdominal pain or distension, meningitis, cellulitis, septic arthritis, infected wound; Presence of any one of: (1) respiratory rate \> 22/min or intubated for respiratory support; (2) acute confusion or reduced level of consciousness; (3) presence of hypotension: SBP\<=100mmHg (comprehensive data set)
Exclusion
- None,
Key Trial Info
Start Date :
January 1 2015
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2040
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04110912
Start Date
January 1 2015
End Date
December 1 2040
Last Update
October 1 2019
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
Hamilton Health Sciences
Hamilton, Ontario, Canada, L8V 1C3
2
Sunnybrook Health Sciences Center
Toronto, Ontario, Canada, M4N 3M5
3
St Michael's Hospital
Toronto, Ontario, Canada, M5V 1W8