Status:

COMPLETED

Simplified Monitoring Myanmar SM2 Study

Lead Sponsor:

Kirby Institute

Collaborating Sponsors:

University of Public Health, Myanmar

Conditions:

Hepatitis C

Liver Cirrhoses

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The study will evaluate the proportion of patients with undetectable HCV RNA at 12 weeks post-treatment (SVR12) following a course of DAA therapy delivered using a simplified schedule of safety and vi...

Detailed Description

A total of 200 HIV/HCV co-infected patients who plan to commence DAA therapy at Specialist Hospital Waibargi and Mingaladon, will be enrolled by simple random sampling. In addition to standard of car...

Eligibility Criteria

Inclusion

  • Subjects must meet all of the following inclusion criteria to participate in this study.
  • Have voluntarily signed the consent form.
  • 18 years of age or older.
  • HCV antibody positive.
  • HIV antibody positive.

Exclusion

  • Subjects who meet any of the exclusion criteria are not to be enrolled in this study.
  • Clinically significant illness (other than HCV) or any other major medical disorder that may interfere with the subject treatment, assessment or compliance with the protocol.
  • Creatinine clearance (CLcr) \< 30mL/min at screening.
  • Pregnant or nursing female.
  • Use of prohibited concomitant medications.
  • Inability or unwillingness to provide informed consent or abide by the study requirements.

Key Trial Info

Start Date :

January 22 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 22 2020

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04113629

Start Date

January 22 2019

End Date

December 22 2020

Last Update

February 21 2021

Active Locations (1)

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The Kirby Institute, University of New South Wales Australia

Sydney, New South Wales, Australia, 2052