Status:
COMPLETED
Exercise and Therapeutic Learning Among Women With PTSD
Lead Sponsor:
University of Wisconsin, Madison
Conditions:
PTSD
Eligibility:
FEMALE
21-50 years
Phase:
NA
Brief Summary
This study aims to test whether aerobic exercise performed after fear extinction learning improves the consolidation and subsequent recall of the learned safety memories (i.e., fear extinction memorie...
Eligibility Criteria
Inclusion
- Current diagnosis of PTSD where the index traumatic event includes physical or sexual assault
- English speaking
- Medically healthy
Exclusion
- Any endorsed medical concerns related to physical activity (as probed in the phone screening questions regarding cardiovascular, pulmonary, or metabolic disease and as assessed via the Physical Activity Readiness Questionnaire (PAR-Q), which probes into participants' history of heart conditions, chest pain, dizziness, loss of consciousness, bone/joint problems, and medication history). Participants would not be excluded if they report this condition being "controlled" or "addressed" through medication or lifestyle change, such as regular exercise.
- Major medical disorders (such as cancer, AIDS)
- Physical discomfort or difficulty with blood draws
- Psychotic disorders
- Intellectual disabilities
- Developmental disorders
- Active substance use disorders
- Pregnancy
- Due to safety concerns, participants with these conditions will be ineligible to participate:
- Major medical disorders (e.g., HIV, cancer)
- Daily cannabis use
- History of light headedness or fainting during blood draws or physical activity
- History of chest pain during physical activity
- Abnormal EKG finding at intake visit screening, without follow-up clearance from their physician
- Bone, joint, cardiac, pulmonary, metabolic, or other medical conditions that may be worsened by physical activity (e.g., Chronic Obstructive Pulmonary Disease (COPD), diabetes, hypertension) that is not currently addressed via medication or lifestyle change.
- A positive pregnancy test
- A self-reported history of loss of consciousness (greater than 30 minutes)
- Physical disabilities that prohibit task performance (such as blindness or deafness)
- Psychotic disorders (e.g., schizophrenia)
- Any other condition that the investigator believes might put the participant at risk
Key Trial Info
Start Date :
April 8 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 21 2020
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT04113798
Start Date
April 8 2019
End Date
January 21 2020
Last Update
June 19 2020
Active Locations (1)
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1
University of Wisconsin
Madison, Wisconsin, United States, 53719