Status:

COMPLETED

Detecting Compartment Syndrome Pain in the Presence of Regional Anesthesia in Healthy Volunteers

Lead Sponsor:

Brigham and Women's Hospital

Collaborating Sponsors:

Massachusetts Institute of Technology

Conditions:

Compartment Syndrome of Leg

Healthy

Eligibility:

All Genders

18-65 years

Phase:

PHASE1

Brief Summary

The goal of the study is to determine how different types of Regional Anesthesia (nerve blocks) can be helpful to patients with lower extremity trauma who develop compartment syndrome (an increased pr...

Detailed Description

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Eligibility Criteria

Inclusion

  • Age ≥ 18 years old, ≤ 65 years old
  • BMI \< 35
  • Able to speak and understand English
  • Willingness to undergo psychophysical testing
  • Willingness to have nerve block performed

Exclusion

  • Ongoing acute or chronic pain in lower extremities
  • Diagnosis of neuropathy
  • Diagnosis of diabetes
  • History of chronic opioid use (having an opioid prescription \> 30 days)
  • Loss of any limb
  • Currently pregnant
  • Any skin conditions or breakdown of skin affecting lower extremities
  • Current history of peripheral arterial disease
  • History of blood clot in any lower extremity
  • Current smoking/vaping of nicotine or illicit substances including marijuana

Key Trial Info

Start Date :

September 29 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 6 2021

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT04113954

Start Date

September 29 2020

End Date

April 6 2021

Last Update

May 14 2021

Active Locations (1)

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1

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02115