Status:
ACTIVE_NOT_RECRUITING
Longitudinal Assessment of Multiple Organs in Patients With Type 2 Diabetes
Lead Sponsor:
Perspectum
Collaborating Sponsors:
University of Liverpool
Liverpool University Hospitals NHS Foundation Trust
Conditions:
Type 2 Diabetes
Eligibility:
All Genders
18+ years
Brief Summary
MODIFY study is a multi-centre prospective, longitudinal, observational cohort study which aims to recruit 150 adult patients with type 2 diabetes recruited from community, primary care or secondary c...
Detailed Description
There has been a surge in incidence of the metabolic syndrome; a cluster of conditions which increase the risk of, type 2 diabetes (T2D) (90% of diabetes cases), non-alcoholic fatty liver disease (NAF...
Eligibility Criteria
Inclusion
- Male or female over 18 years of age and diagnosed with type 2 diabetes.
- Participant currently taking glucose lowering therapy.
- Participant willing and able to give informed consent for participation in the study.
Exclusion
- The participant may not enter the study if they have any contraindication to magnetic resonance imaging (standard MR exclusion criteria including pregnancy, extensive tattoos, pacemaker, shrapnel injury, severe claustrophobia).
- Patients with known autoimmune hepatitis, viral hepatitis, Wilson's disease, haemoglobinopathies or significant structural renal tract abnormality.
- Patients with known excessive alcohol intake.
- Any other cause, including a significant disease or disorder which, in the opinion of the investigator, may either put the participant at risk because of participation in the study, or may influence the participant's ability to participate in the study.
Key Trial Info
Start Date :
January 27 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 30 2026
Estimated Enrollment :
135 Patients enrolled
Trial Details
Trial ID
NCT04114682
Start Date
January 27 2020
End Date
September 30 2026
Last Update
December 1 2025
Active Locations (4)
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1
Aintree University Hospital NHS Foundation Trust
Liverpool, Merseyside, United Kingdom, L9 7AL
2
Oxford University Hospitals NHS Foundation Trust
Oxford, Oxfordshire, United Kingdom, OX3 7LE
3
Perspectum Ltd.
Oxford, Oxfordshire, United Kingdom, OX4 2LL
4
Royal Free Hospital NHS Foundation Trust
London, United Kingdom, NW3 2QG