Status:

UNKNOWN

A Retrospective Cohort Study on the Risk of Serious Infections in Rheumatoid Arthritis Patients Receiving Tocilizumab

Lead Sponsor:

Sungkyunkwan University

Collaborating Sponsors:

Ministry of Food and Drug Safety, Korea

Conditions:

Infection

Rheumatoid Arthritis

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to evaluate whether the risk of serious infections in rheumatoid arthritis patients with tocilizumab is higher than in those with tumor necrosis factor inhibitors using th...

Detailed Description

This observational, retrospective cohort study using the Korean National Health Insurance (NHI) data will evaluate whether the risk of serious infections (SIs) in rheumatoid arthritis patients treated...

Eligibility Criteria

Inclusion

  • Individuals who had a diagnosis of rheumatoid arthritis (ICD-10 codes: M05-06) between 2013 and 2018

Exclusion

  • Individuals less than 18 years of age
  • Having no records of prescription of tocilizumab or TNFi at least once between 2013 and 2018

Key Trial Info

Start Date :

April 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 1 2021

Estimated Enrollment :

9508 Patients enrolled

Trial Details

Trial ID

NCT04115423

Start Date

April 1 2020

End Date

October 1 2021

Last Update

September 10 2020

Active Locations (1)

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Sungkyunkwan University

Suwon, Gyeonggi-do, South Korea, 16419