Status:
COMPLETED
The Effect of Different Starches of Boba Pearls and Sugar Substitutes Used in Milk Tea on Glycaemia, Insulinaemia and Appetite Control (Pearl Study)
Lead Sponsor:
Singapore Institute of Food and Biotechnology Innovation
Conditions:
Diabete Type 2
Obese
Eligibility:
MALE
21-40 years
Phase:
NA
Brief Summary
The first objective is to investigate the effect of boba pearls made from different starches on glycaemia, insulinaemia and appetite control. The second objective is to investigate the effects of vari...
Detailed Description
Design: There are two parts to this study. Participants will voluntarily choose to participate in either one or both parts of the study during the first screening session. Part A: Testing the effects ...
Eligibility Criteria
Inclusion
- Males
- Healthy Asian Chinese
- Aged between 21 - 40 years
- ≥45kg body weight
- Body mass index between 18.5 to 25.0 kg/m2
- Normal blood pressure ≤140/90 mmHg
- Fasting blood glucose \<5.6 mmol/L
Exclusion
- Smoking
- Allergic/intolerant to any of the test foods to be administered, or any of the following common food and ingredients: eggs, fish, milk, peanuts, tree nuts, shellfish, soya, wheat, gluten, cereal, fruits, dairy products, meat, vegetable, sugar and sweetener, natural food colourings or flavourings, sulphites etc.
- Anyone with intentional food restrictions
- People with known glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency)
- Having metabolic or cardiovascular diseases (such as diabetes, hypertension, heart condition, etc.)
- Having medical conditions and/or taking medications known to affect glycaemia (glucocorticoids, thyroid hormones, thiazide diuretics)
- Taking any prescribed medication or dietary supplements which may interfere with the study measurements
- Individuals who have any major organ dysfunction (eg. cardiovascular, respiratory, hepatic, renal, gastrointestinal) that may influence taste, olfaction, appetite, digestion, metabolism, absorption or elimination of test foods, nutraceutical or drug
- Excessive alcohol consumption: consuming ≥ 6 alcoholic drinks per week
- Have known Chronic infection or known to suffer from or have previously suffered from or is a carrier of Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Immunodeficiency Virus (HIV)
- Have active Tuberculosis (TB) or currently receiving treatment for TB
- Individuals who partake in sports at the competitive and/or endurance levels
- A team member of the study or is an immediate family member (Immediate family defined as a spouse, parent, child, or sibling, whether biological or legally adopted)
Key Trial Info
Start Date :
May 2 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 30 2022
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT04115657
Start Date
May 2 2019
End Date
December 30 2022
Last Update
August 31 2023
Active Locations (1)
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1
Clinical Nutrition Research Centre
Singapore, Singapore, 117599