Status:

UNKNOWN

DIEP Flap Perfusion Evaluated by DIRT and ICG-FA.

Lead Sponsor:

University Hospital of North Norway

Collaborating Sponsors:

UiT The Arctic University of Norway

Conditions:

Reconstructive Surgical Procedures

Eligibility:

FEMALE

25-70 years

Brief Summary

Patients selected for DIEP breast reconstruction were examined with preoperative CTA, Doppler Ultrasound, dynamic infrared thermography (DIRT) and Indocyanin green fluorescent angiography (ICG-FA) for...

Detailed Description

Introduction: 'The primary aim of our study is to compare invasive and non-invasive techniques to select a dominant perforator when harvesting a DIEP-flap for autologous breast reconstruction. The s...

Eligibility Criteria

Inclusion

  • Post mastectomy.
  • Previously breast cancer patent treated with radiation therapy.
  • Breast implant reconstruction is not possible or undesired.
  • Healthy patient with moderate amounts of abdominal skin laxity.
  • Patient who requires a minimal to moderate volume breast reconstruction.
  • The patient willing to undergo the long, complex procedure and prolonged postoperative recovery.
  • The patient willing to accept an abdominal scar and a potential for donor site morbidities.
  • Patients operated with prophylactic salpingo-oophorectomy due to BRCA gene mutation.

Exclusion

  • Pregnancy and lactation.
  • Patents below the age of 18 year.
  • Renal failure or hepatic failure.
  • Previous allergic reactions to ICG and iodide.
  • Abdominal donor site that cannot be closed primarily.
  • Previous TRAM flap or abdominoplasty.
  • Significant medical comorbidities that make the patient a poor surgical candidate.
  • Sigarette smoking or snuff.
  • Obesity / BMI \> 30.
  • Previous abdominal suction-assisted lipectomy.

Key Trial Info

Start Date :

January 16 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2019

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04115995

Start Date

January 16 2019

End Date

December 31 2019

Last Update

October 4 2019

Active Locations (1)

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Univesity Hospital of North Norway

Tromsø, Norway, 9038