Status:
COMPLETED
Muscular Respiratory Involvement and Systemic Sclerosis
Lead Sponsor:
Poitiers University Hospital
Conditions:
Systemic Sclerosis
Diaphragm Defect
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Dyspnea in systemic sclerosis (ScS) constitute a major factor of functional disability. Intensity of dyspnea is sometimes discordant with objectives data from cardiopulmonary involvements, suggesting...
Eligibility Criteria
Inclusion
- Age ≥18 years-old
- ScS fulfilling ACR/EULAR 2013 classification criteria and followed in the department of internal medicine of Poitiers University Hospital
- Written informatory consent
Exclusion
- Individuals under tutorship or guardianship
- Individuals with reinforced protection: minors, judiciary or administrative decision
- No affiliation to social insurance
- Pregnancy or breastfeeding
- Associated neuromuscular disease (myasthenia, degenerative diseases)
- Bedridden individuals or with health condition not allowing realization or interpretation of PFT and/or EMG (acute cardiac and/or respiratory failure, pneumopathy)
- Individuals with pacemaker and implanted pumps, especially sensing dispositives, as defibrillators ( relative contre-indication to EMG with magnetic stimulation)
- Individuals with contre-indication to gastroesophageal probe: INR \>4, oesophageal varices, suspected cardio-facial fracture, oesophageal and/or facial obstacle
Key Trial Info
Start Date :
October 21 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 7 2021
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT04118725
Start Date
October 21 2019
End Date
July 7 2021
Last Update
September 29 2021
Active Locations (1)
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1
Chu de Poitiers
Poitiers, France