Status:

UNKNOWN

Observational Study on Inappropriate Therapies

Lead Sponsor:

MicroPort CRM

Conditions:

Inappropriate Shocks From Implanted Defibrillator

ICD Replacement or Upgrade

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of the study is to assess the incidence of inappropriate shocks at 2 years, in a population of patients undergoing a generator replacement (VR/DR/CRT) or upgrade from a previously implante...

Detailed Description

All subjects will be included during an inclusion visit (within 7 days post generator replacement or upgrade), and followed up at a post replacement visit (1 - 6 months post replacement or upgrade), a...

Eligibility Criteria

Inclusion

  • Any subject that had an ICD/CRT-D replacement/upgrade according to the latest relevant clinical guidelines with a MicroPort CRM ICD / CRT-D for less than 7 days
  • Signed and dated the informed consent form

Exclusion

  • RV lead replacement
  • Previous ICD/CRT-D inactivated or already explanted
  • Active myocarditis
  • Primary prevention for Arrhythmogenic Ventricular Cardiomyopathy, Ion channelopathies, Hypertrophic Cardiomyopathy and Infiltrative or Inherited Cardiomyopathy.
  • Heart transplant (done or on waiting list) or implanted with a ventricular assist device (VAD)
  • Already included in an Interventional study that could confound the results of this study
  • Inability to understand the purpose of the study or to meet follow-up visits as defined in the investigational plan
  • Minor age (\<18 years) or under guardianship or kept in detention
  • Ongoing drug or alcohol addiction or abuse which would interfere with the subject's ability to be compliant with the study.
  • Life expectancy less than 1 year
  • Pregnant or breast feeding

Key Trial Info

Start Date :

January 31 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 30 2025

Estimated Enrollment :

881 Patients enrolled

Trial Details

Trial ID

NCT04118803

Start Date

January 31 2020

End Date

May 30 2025

Last Update

June 5 2023

Active Locations (58)

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Page 1 of 15 (58 locations)

1

Broward Health Medical Center

Fort Lauderdale, Florida, United States, 33316

2

The University of Chicago Medicine Hospital

Chicago, Illinois, United States, 60637

3

Loyola University Medical Center

Maywood, Illinois, United States, 60153

4

Rutgers New Jersey Medical School

Newark, New Jersey, United States, 07103