Status:
UNKNOWN
Correlation of Serum Level of Perampanel (PER) Level to Cerebrospinal Fluid (CSF) Levels of PER
Lead Sponsor:
Carilion Clinic
Conditions:
Epilepsy
Seizures
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Perampanel is a drug used to treat patients with epilepsy/seizures. This study is designed to determine how much perampanel actually crosses the blood brain barrier into the cerebral spinal fluid when...
Detailed Description
Perampanel is a drug used to treat patients with epilepsy/seizures. This study is designed to determine how much perampanel actually crosses the blood brain barrier into the cerebral spinal fluid when...
Eligibility Criteria
Inclusion
- Adults (\>18 years-old) who are scheduled to undergo brain surgery and need antiepileptic medication for prophylaxis or treatment of seizures
- Able to provide informed consent
Exclusion
- Patient unable to provide informed consent
- Allergy to PER or its component
- Patient with significant renal (creatinine clearance 35 ml/min) or hepatic impairment
- Pregnant or lactating females will be excluded from the study.
Key Trial Info
Start Date :
November 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2023
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT04118829
Start Date
November 1 2019
End Date
March 1 2023
Last Update
September 16 2021
Active Locations (1)
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1
Carilion Clinic
Roanoke, Virginia, United States, 24016