Status:
UNKNOWN
Use of GDF15 as a Biomarker for Early Diagnosis of DM and Monitoring of Progress of Complications in Asians
Lead Sponsor:
Chang Gung Memorial Hospital
Conditions:
Diabetes Mellitus, Type 2
Diabetic Polyneuropathy
Eligibility:
All Genders
20+ years
Brief Summary
Significant differences in the expression of individual Growth Differentiation Factor 15 (GDF-15) proteins among Taiwanese harboring different mitochondrial genotypes are noted, and their blood serum ...
Detailed Description
Previous studies have confirmed that mitochondria are associated with insulin resistance or diabetes. As the prevalence of type 2 diabetes mellitus (T2DM) continues to increase worldwide, early detect...
Eligibility Criteria
Inclusion
- adult participants with age \>20, with pre-DM or DM as the study group and participants without hyperglycemia as the control group
Exclusion
- Pregnant woman or who is under breastfeeding
- Who is difficult to understand or sign the informed consent
- With coagulopathy or hematologic disease
Key Trial Info
Start Date :
August 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 30 2021
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT04119167
Start Date
August 1 2019
End Date
October 30 2021
Last Update
October 8 2019
Active Locations (1)
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1
Chang Gung Memorial Hospital
Kaohsiung City, Taiwan