Status:

RECRUITING

Autoimmunity After Checkpoint Blockade

Lead Sponsor:

Abramson Cancer Center at Penn Medicine

Conditions:

Autoimmunity

Cancer

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to better understand how the treatment of cancer with immune checkpoint inhibitors (ICI) leads to the development of autoimmunity. Specifically, we wish to understand the ...

Detailed Description

The goal of this study is to understand how the treatment of cancer with checkpoint inhibitors leads to the development of autoimmunity. Specifically, to understand the genetics and immune system feat...

Eligibility Criteria

Inclusion

  • A diagnosis of cancer and prescription for a checkpoint inhibitor

Exclusion

  • Any subjects not willing or able to give consent
  • Children under the age of 18
  • A history of transplant

Key Trial Info

Start Date :

February 24 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 30 2026

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT04119713

Start Date

February 24 2020

End Date

June 30 2026

Last Update

January 8 2026

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Pennsylvania - Abramson Cancer Center

Philadelphia, Pennsylvania, United States, 19104

Autoimmunity After Checkpoint Blockade | DecenTrialz