Status:

COMPLETED

Effect of Curcumin on Microvascular Response and Tissue Oxygenation

Lead Sponsor:

Universidade Federal do Rio de Janeiro

Conditions:

Cardiovascular Risk Factor

Eligibility:

All Genders

60-85 years

Phase:

NA

Brief Summary

Aging has been associated with reduced bioavailability of nitric oxide(NO) and endotelial dysfunction.Curcumin, a phenolic compound present in the rhizomes of turmeric, possesses cardiovascular protec...

Detailed Description

Aging has been associated with reduced bioavailability of nitric oxide(NO) and endotelial dysfunction. Curcumin, a phenolic compound present in the rhizomes of turmeric, possesses cardiovascular prot...

Eligibility Criteria

Inclusion

  • Seniors,
  • With two or more risk factors for cardiovascular disease:Dyslipidemia, visceral obesity, hypertension, diabetes mellitus 2 and others.

Exclusion

  • Smoking,
  • Use of antioxidant drugs during the experiment period,
  • Allergy to components of curcumin,
  • With previous history of cancer, HIV,
  • Neurodegenerative and osteomioarticular diseases.

Key Trial Info

Start Date :

January 4 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 24 2020

Estimated Enrollment :

28 Patients enrolled

Trial Details

Trial ID

NCT04119752

Start Date

January 4 2019

End Date

June 24 2020

Last Update

June 26 2020

Active Locations (1)

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1

Central Coexistence of the Elderly

Macaé, Rio de Janeiro, Brazil