Status:
UNKNOWN
Discovery for Biomarkers and Risk Factors for Postoperative Delirium in Elderly Patients With Spine Surgery
Lead Sponsor:
Yonsei University
Conditions:
Spinal Disease
Eligibility:
All Genders
70-100 years
Brief Summary
Introduction: With the increase of the elderly population, the number of elderly patients undergoing surgery is increasing, and postoperative delirium is 11-51% depending on the type of surgery. In re...
Detailed Description
Method: 1. Study design: This study is a prospective investigation that identifies risk factors for postoperative delirium and searches for predictive biomarkers of delirium. 2. Inclusion criteria / ...
Eligibility Criteria
Inclusion
- Elderly patients over 70
- Eligible Surgeries: lumbar spine fusion surgery, posterior cervical spine fusion surgery, or anterior cervical spine fusion surgery
Exclusion
- Patients with cognitive decline according to MMSE-DS outcome criterion
- Patients diagnosed with malignant or benign tumors
- If surgery is scheduled within 2 hours(micro surgery)
- In case of difficulty in communication
- History of brain neurological diseases (brain hemorrhage, stroke, dementia, Parkinson's, cognitive impairment diagnosis, etc.)
- Patients diagnosed with alcoholism or drug addiction
- Patients with surgical complications (post-operative bleeding, high fever over 39 degrees, etc.)
- Patients undergoing re-operation due to surgery-related complications
Key Trial Info
Start Date :
October 21 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2021
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT04120272
Start Date
October 21 2019
End Date
October 1 2021
Last Update
June 7 2021
Active Locations (1)
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1
Severance Hospital, Yonsei University Health System
Seoul, South Korea