Status:
RECRUITING
DNA Repair Activity in the Skin of Day and Night Shift Workers
Lead Sponsor:
Wright State University
Conditions:
Skin Cancer
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
The purpose of this study is to test how the skin of night shift workers responds to artificial sunlight (ultraviolet B radiation; UVB) at two different times of the day in comparison to normal day sh...
Eligibility Criteria
Inclusion
- Male/Female
- Fair skin (Fitzpatrick types I and II)
- Age 18 to 40
- Able to comprehend procedures/risks
- Primarily work and are awake during normal daylight hours (6 am to 6 pm), or primarily work and are awake during night shifts hours (between the hours of 6 pm and 6 am) or may work a mixture of these shifts over the past 3 months. Rotating shifts will be categorized based on the majority of hours worked on average during the last 3 months. Able to fill out a 3-month calendar of work schedule.
Exclusion
- Known photosensitivity
- Currently on photosensitizing medications
- Diabetes Mellitus
- On any hormonal agents (e.g., birth control pills)
- History of abnormal scarring
- History of skin infections
- History of skin cancers
- History of sleep disorders such as sleep apnea or insomnia
- Known allergy to lidocaine local anesthetic
- Pregnancy or nursing
- Other serious health issues
Key Trial Info
Start Date :
December 7 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT04122456
Start Date
December 7 2022
End Date
December 1 2025
Last Update
February 6 2025
Active Locations (1)
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1
Wright State Physicians
Fairborn, Ohio, United States, 45324