Status:
SUSPENDED
Metabotypes in the Urinary Excretion of Flavan-3-ol Metabolites: "Metanols"
Lead Sponsor:
University of Parma
Collaborating Sponsors:
Azienda Ospedaliero-Universitaria di Parma
Conditions:
Diet Modification
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Flavan-3-ols are the main source of flavonoids in Western diets. They are characteristic compounds of tea, cocoa, wine, apple, pears, etc. In plant-based foods, they occur as simple monomers or as oli...
Detailed Description
The study will be a single-dose, partially randomized, cross-over design, with 4 consecutive treatments. The study includes 4 phases where each volunteer will consume a specific dose of one of the pro...
Eligibility Criteria
Inclusion
- Adult
- Both genders
- Healthy
- BMI \> 18.5
- BMI \< 30
Exclusion
- Metabolic disorder or surgeries of liver, kidney or gastrointestinal tract
- Immunodeficiency
- Food intolerance or allergies
- Regular consumption of medication
- Antibiotic therapy within the last 3 months
- Use of food supplements, including pro- and prebiotics
- Intense physical activity (PAL ≥ 2.10)
- Pregnancy
- Lactation
Key Trial Info
Start Date :
September 2 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 27 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04124016
Start Date
September 2 2019
End Date
December 27 2022
Last Update
April 30 2021
Active Locations (1)
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1
University of Parma
Parma, Italy, 43125