Status:

COMPLETED

Level of FeNO in Chinese Asthma Patients

Lead Sponsor:

Chinese University of Hong Kong

Conditions:

Asthma

Eligibility:

All Genders

18+ years

Brief Summary

This study aims to assess the level of FeNO in Chinese asthma patients with respect to the different levels of asthma control over 1 year.

Detailed Description

Introduction Measurement of fractional nitric oxide (NO) concentration in exhaled breath (FeNO) has been shown to be a non-invasive, quantitative biomarker related to airway inflammation. Although the...

Eligibility Criteria

Inclusion

  • Chinese subjects aged between 18 and 90 years, and
  • Have a diagnosis of asthma according to The Global Initiative for Asthma (GINA) guideline 2019. Asthma is defined as those with a consistent history and prior documented evidence of variable airflow obstruction, with evidence of an increase in FEV1 greater than 12% or 200 mL following bronchodilator or bronchial hyperresponsiveness on bronchial provocation testing, when stable.

Exclusion

  • Patients with respiratory diseases with other known respiratory diseases including chronic obstructive pulmonary disease, bronchiectasis, tuberculosis (TB)-destroyed lung parenchyma, history of lung resection and lung cancer
  • Individuals older than 40 years with a smoking history of more than 10 pack-years
  • Patients currently randomized in other clinical studies
  • Pregnant women

Key Trial Info

Start Date :

October 15 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2022

Estimated Enrollment :

132 Patients enrolled

Trial Details

Trial ID

NCT04125316

Start Date

October 15 2019

End Date

December 31 2022

Last Update

February 8 2023

Active Locations (1)

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The Chinese University of Hong Kong

Hong Kong, Hong Kong