Status:
UNKNOWN
Mediastinoscopy-assisted Transhiatal Esophagectomy Versus Thoraco-laparoscopic Esophagectomy for Esophageal Cancer
Lead Sponsor:
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Collaborating Sponsors:
Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center
Peking University Cancer Hospital & Institute
Conditions:
Esophageal Neoplasms
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Esophageal cancer is one of the major diseases that seriously threatens an individual's health and life. To reduce the incidence of postoperative complications and mortality of esophageal cancer, thor...
Detailed Description
Esophageal resection remains the mainstay of treatment for esophageal cancer patients. Despite improvements in surgical technique and perioperative management, esophagectomy carries considerable opera...
Eligibility Criteria
Inclusion
- 18 years≤age≤ 80 years;
- Histologically diagnosed with squamous cell carcinoma by endoscopic biopsy, cT1-3N0M0;
- Primary tumour is located in the thoracic oesophagus
- No clinical evidence of distant organ metastasis
- No severe comorbidity, can tolerate anesthesia;
- ECOG PS scores≤2;
- The patients sign informed consents by themselves.
Exclusion
- Cervical or abdominal oesophageal carcinoma;
- Previous oesophagectomy, gastrectomy, or mediastinal surgery;
- Current uncontrolled illness such as severe cardiac disease, uncontrollable hypertension or diabetes, or active bacterial infection;
- Unable to tolerate tracheal intubation and general anaesthesia as determined by an anaesthesiologist preoperatively;
- Pregnant or lactating women;
- ECOG PS scores\>2;
- Considered unsuitable, such as those who do not agree to participate in the trial.
Key Trial Info
Start Date :
April 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT04125849
Start Date
April 1 2020
End Date
December 1 2022
Last Update
April 15 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Cancer Hospital of Chinese Academy of Medical Sciences Shenzhen Center
Shenzhen, Guangdong, China, 518000