Status:
RECRUITING
Comparative Imaging Assessment of Valvular Heart Disease
Lead Sponsor:
The Cleveland Clinic
Conditions:
Valve Heart Disease
Aortic Stenosis
Eligibility:
All Genders
18-90 years
Brief Summary
The purpose of the study is to compare the various 2D and 3D methods of valvular heart disease quantification (Doppler, PISA, VCA, volumetric method) and strain with cardiac magnetic resonance (CMR) m...
Detailed Description
The objective of this study is to compare the accuracy of 3D TTE to 2D TTE in assessing the severity of valvular heart disease in patients with aortic stenosis, aortic regurgitation, and mitral valve ...
Eligibility Criteria
Inclusion
- Age 18-90 years of age
- Suspected moderate or severe MR,AR or AS on the basis of prior known clinical history or clinical exam.
- Suspected CRT "non-responder" with an implanted MRI compatible CRT device and reduced ejection fraction
Exclusion
- Acute traumatic cardiac injury
- Aortic dissection or aortic root rupture
- Congenital heart diseases such as patent ductus arteriosus, coarctation of aorta, ASD and VSD
- Presence of A-V fistula or intracardiac shunts
- Any contraindications to CMR
- Moderate or severe dysfunction in multiple valves
- Patients with significant claustrophobia
Key Trial Info
Start Date :
August 23 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04126018
Start Date
August 23 2019
End Date
June 30 2026
Last Update
January 2 2026
Active Locations (1)
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1
Cleveland Clinic
Cleveland, Ohio, United States, 44195