Status:
COMPLETED
Effect of Adjunctive Systemic Vitamin E on Clinical Parameters and Salivary Total Antioxidant Capacity in Symptomatic Oral Lichen Planus Patients: Randomized-controlled Clinical Trial
Lead Sponsor:
Cairo University
Conditions:
Oral Lichen Planus
Eligibility:
All Genders
Phase:
PHASE1
Brief Summary
Treatment of oral lichen planus is challenging. Diverse therapeutic modalities have been suggested, but a permanent cure is not yet available. In some oral lichen planus patients, topical corticoster...
Detailed Description
The current study is a randomized-controlled clinical trial that follows CONSORT guideline. The current trial include 30 symptomatic OLP patients in two parallel groups (intervention - topical triamci...
Eligibility Criteria
Inclusion
- Patients clinically and histopathologically diagnosed as suffering from OLP (erosive and atrophic OLP patients who agreed to take supplied medications).
- Patients free from any visible oral lesions other than OLP.
- Patients who agreed to take supplied medications.
- Patients who agreed for the biopsy
Exclusion
- Reticular OLP patients
- Patients suffering from any systemic disease.
- Patients Treated with any systemic treatment such as systemic steroids, other immunosuppressive drugs or non-steroidal anti-inflammatory drugs at least eight weeks.
- Treatment with any oral topical medications for at least four weeks prior to the study.
- Pregnant and lactating mothers
Key Trial Info
Start Date :
January 22 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 12 2017
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04126720
Start Date
January 22 2016
End Date
November 12 2017
Last Update
October 22 2019
Active Locations (1)
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1
Faculty of Dentistry Cairo University
Giza, Egypt, 12345