Status:

UNKNOWN

Next Generation Sequencing(NGS)Monitors Minimal Residual Disease(MRD)in Allo-PBSCT Patients

Lead Sponsor:

Xianmin Song, MD

Conditions:

NGS Monitor MRD

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

Objective: to evaluate the value of high-throughput next generation gene sequencing (NGS) in the detection of minimal residual disease (MRD) and recurrence after allogeneic transplantation. Overview ...

Detailed Description

Minimal residual disease (MRD) detection is the detection of residual micro-clones in patients with leukemia in remission, predicting the recurrence of the disease, and determining the next treatment ...

Eligibility Criteria

Inclusion

  • ≥18 years old, male or female;
  • Patients who received allogeneic peripheral blood hematopoietic stem cell transplantation ;
  • Patients must be able to understand and be willing to participate in this study and sign informed consent.-

Exclusion

  • Non-allogeneic hematopoietic stem cell transplantation patients;
  • The expected survival rate is less than 3 months after transplantation;

Key Trial Info

Start Date :

October 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2023

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04126967

Start Date

October 1 2019

End Date

December 31 2023

Last Update

October 15 2019

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Shanghai General Hospital

Shanghai, Shanghai Municipality, China, 200080