Status:
COMPLETED
An Exploratory Study of Continuous Theta Burst Stimulation (cTBS) Based on fMRI in the Treatment of Tic Disorder
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University
Collaborating Sponsors:
Hangzhou Normal University
Conditions:
Tic Disorders
Tourette Syndrome
Eligibility:
All Genders
6-20 years
Phase:
NA
Brief Summary
continuous theta burst stimulation (cTBS) is a safe and effective device for Gilles de la Tourette's syndrome treatment. GPi is an agreed curative target of deep brain stimulation. GPi-based functiona...
Detailed Description
Tic disorder is a common neuropsychiatric disorder in children and adolescents. Medication is not effective and has side effect. Exploring new treatment methods is one of the research pathway of this ...
Eligibility Criteria
Inclusion
- meet the diagnostic criteria of chronic tic disorder or tourette syndrome;
- Yale Global Tic Severity Scale (YGTSS) score is greater than 20;
- the symptoms lasted more than 1 year, and the drug regimen was not adjusted within one month;
- right-handedness;
- age 6-20 years;
- able to receive continuous theta burst stimulation (cTBS) therapy, participants and their guardians agree to receive treatment and observation.
Exclusion
- age is under 6-year old;
- can not tolerate MRI or cTBS treatment;
- adjust medication during treatment.
Key Trial Info
Start Date :
June 29 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2019
Estimated Enrollment :
95 Patients enrolled
Trial Details
Trial ID
NCT04128397
Start Date
June 29 2018
End Date
December 31 2019
Last Update
August 5 2022
Active Locations (2)
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1
center for cognition and brain disorders,HZNU
Hangzhou, Zhejiang, China, 310000
2
2nd Affiliated Hospital, School of Medicine, Zhejiang University
Hanzhou, Zhejiang, China, 310000