Status:
UNKNOWN
Selegiline and Reward Processing
Lead Sponsor:
University of Oxford
Conditions:
Healthy
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
There has been growing interest in the relationship between reward processing and clinical symptoms of depression such as anhedonia (loss of interest and response to pleasurable activities). The aim ...
Detailed Description
There has been growing interest in the relationship between reward processing and clinical symptoms of depression such as anhedonia (loss of interest and response to pleasurable activities). Studies i...
Eligibility Criteria
Inclusion
- 18-40 years of age
- Able to give informed consent for study participation
- Sufficient fluency in English to understand and complete the neuropsychological tasks
Exclusion
- Current usage of other regular medication (including the contraceptive pill, the Depo-Provera injection or the progesterone implant, and hormone replacement therapy)
- Any past or current Axis 1 DSM-IV psychiatric disorder
- Significant medical condition
- Pulse \< 60 beats per minute at baseline screening
- Current or past gastro-intestinal disorder or irritable bowel syndrome
- Current pregnancy or breastfeeding
- Known lactate deficiency or any other problem absorbing lactose, galactose or glucose
- Current or past history of drug or alcohol dependency
- Participation in a psychological or medical study involving the use of medication within the last 3 months
- Previous participation in a study using the same, or similar, emotional processing tasks
- Smoker \> 5 cigarettes per day
- Typically drinks \> 6 caffeinated drinks per day
Key Trial Info
Start Date :
September 18 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 10 2020
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT04130087
Start Date
September 18 2019
End Date
September 10 2020
Last Update
October 17 2019
Active Locations (1)
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1
University of Oxford
Oxford, Oxfordshire, United Kingdom, OX3 7JZ