Status:
ACTIVE_NOT_RECRUITING
Promotion of Weight Management
Lead Sponsor:
VA Office of Research and Development
Collaborating Sponsors:
Baltimore VA Medical Center
South Texas Veterans Health Care System
Conditions:
Overweight
Eligibility:
All Genders
50-75 years
Phase:
NA
Brief Summary
The identification of intermittent fasting as an alternative method to traditional weight maintenance protocols could have a significant impact on preventing body weight regain common after successful...
Detailed Description
The research will examine the impact of intermittent fasting to promote long term body weight maintenance following successful weight loss in overweight and obese Veterans. This research is especially...
Eligibility Criteria
Inclusion
- Veteran
- 50-75 years of age
- BMI: 25-40 kg/m2
- Postmenopausal status for women
Exclusion
- Uncontrolled diabetes (HbA1c \>10% or the current use of insulin)
- Neurologic, musculoskeletal, or other condition that limits subject's ability to complete study physical assessments
- Active inflammatory, autoimmune, infectious, hepatic, gastrointestinal, malignant, and psychiatric disease
- Weight change within the past month of \>5 kg
- Self-reported alcohol or drug abuse
- Anti-coagulant medication for muscle biopsies only Impaired renal function (creatinine \> 1.5 mg/dl) History or evidence of serious liver disease (LFTs \> 2.5 x WNL)
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 7 2026
Estimated Enrollment :
175 Patients enrolled
Trial Details
Trial ID
NCT04131647
Start Date
March 1 2021
End Date
January 7 2026
Last Update
September 5 2025
Active Locations (2)
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1
Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD
Baltimore, Maryland, United States, 21201
2
South Texas Health Care System, San Antonio, TX
San Antonio, Texas, United States, 78229