Status:

COMPLETED

Evaluating Whether Integration of Prognostic and Predictive Algorithms Into Routine Clinical Practice Effect Whether Oncologists Order Multigene Assays in Patients With Early Stage Breast Cancer

Lead Sponsor:

Ottawa Hospital Research Institute

Conditions:

Breast Cancer

Eligibility:

All Genders

18+ years

Brief Summary

A broad range of prognostic and predictive tools are available for patients with newly diagnosed early stage breast cancer. These range from free and publicly available mathematical algorithms, throug...

Detailed Description

A broad range of prognostic and predictive tools are available for patients with newly diagnosed early stage hormone receptor positive, Her2 negative breast cancer. These range from free and publicly ...

Eligibility Criteria

Inclusion

  • Histologically confirmed primary breast cancer
  • No prior chemotherapy
  • Eligible for Oncotype DX ® testing as per current Ontario funding criteria including: ER positive, PR positive or negative, HER2 negative, lymph node status negative or micro-invasive disease, tumor \>1 cm in size (or if equal or \<1 cm, must be grade 2/3 or have lymph node micrometastasis).

Exclusion

  • Neoadjuvant treatment including window of opportunity trials
  • Recurrent breast cancer

Key Trial Info

Start Date :

March 6 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 18 2022

Estimated Enrollment :

602 Patients enrolled

Trial Details

Trial ID

NCT04131933

Start Date

March 6 2020

End Date

May 18 2022

Last Update

December 23 2025

Active Locations (6)

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Page 1 of 2 (6 locations)

1

Kingston Health Sciences Centre

Kingston, Ontario, Canada, K7L 2V7

2

Grand River Hospital

Kitchener, Ontario, Canada, N2G 1G3

3

Markham Stouffville Hospital

Markham, Ontario, Canada, L3P 7P3

4

Ottawa Hospital Research Institute

Ottawa, Ontario, Canada