Status:
UNKNOWN
Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC)
Lead Sponsor:
Azienda Sanitaria-Universitaria Integrata di Udine
Conditions:
Therapeutic Drug Monitoring
Subarachnoid Hemorrhage
Eligibility:
All Genders
18+ years
Brief Summary
A recent prospective observational clinical study conducted in an intensive care unit of a third level US university hospital showed that 94% of patients with ES and 50% of those with EC had an ARC fo...
Detailed Description
Haemorrhagic stroke is a devastating disease with a high rate of disability and mortality. In addition to the direct effects of the haemorrhagic event and to the secondary neurological complications, ...
Eligibility Criteria
Inclusion
- Patients of both sexes \> 18 years admitted for ES or EC
- Patients to which one or more water-soluble antibiotics, antifungals or antivirals subject of the present study are prescribed
- Patients who present ARC
Exclusion
- Patients in whom the plasma samples are contaminated
- Patients in whom the plasma samples are performed in a way that does not comply with the prepared company protocol.
- Patients with BMI \< 18 kg / m2.
- Patients with a serum creatinine \> 1.4 mg / dL at entry
- Pregnant patients.
Key Trial Info
Start Date :
October 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2021
Estimated Enrollment :
104 Patients enrolled
Trial Details
Trial ID
NCT04132115
Start Date
October 1 2019
End Date
October 1 2021
Last Update
July 21 2021
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Anesthesiology and Intensive Care Clinic - Department of Medicine - ASUIUD
Udine, Italy, 33100
2
Terapia Intensiva 1
Udine, Italy, 33100