Status:
COMPLETED
Optical Coherence Tomography Angiography in Myopic Patients
Lead Sponsor:
Minia University
Conditions:
Myopia
Eligibility:
All Genders
18-45 years
Brief Summary
The aim of this study is to investigate the macular microvascular network alterations in high myopic eyes using optical coherence tomography angiography.
Detailed Description
High myopia is defined as a refractive error equal to or more than -6 D, and/or axial length equal to or more than 25.5 mm².Axial elongation of the globe and subsequent stretch of the retina leads to ...
Eligibility Criteria
Inclusion
- • Highly myopic subjects, defined as those with spherical equivalents (SEs) of -6 or more, with axial length greater than 26.5 mm.
- Group B individuals were chosen among healthy age-matched controls.
Exclusion
- • Patients younger than 18 years old, or older than 45 years.
- Any patient with macular pathology (e.g. diabetic retinopathy, hypertensive retinopathy, dystrophy)
- Myopic patients with any vitro-retinal abnormalities (e.g. choroidal neovascular membrane (CNVM), foveoschisis,macular hole)
- Patients who underwent previous intra ocular surgical procedures.
- Patients with previous history of intraocular injections.
- Glaucomatous patients.
- Exclusion criteria to the images that has been captured:
- \- Low signal strength index (less than 50).
- \- Presence of blink artefacts.
- \- Poor fixation leading to motion or doubling artefacts.
- \- Media opacity obscuring view of the vasculature.
- \- Segmentation error due to cystoid macular oedema or epi-retinal membrane, among others.
Key Trial Info
Start Date :
January 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2019
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT04135209
Start Date
January 1 2018
End Date
June 1 2019
Last Update
October 22 2019
Active Locations (1)
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1
Minia University
Minya, Minya Governorate, Egypt, 61111