Status:

COMPLETED

Preload Optimization Guided by Inferior Vena Cava Collapsibility Index

Lead Sponsor:

General Hospital of Ningxia Medical University

Conditions:

Adverse Effect

Eligibility:

FEMALE

18-40 years

Phase:

NA

Brief Summary

The purpose of this study is to investigate the optimal preload guided by inferior vena cava collapsibility index in parturients with prophylactic norepinephrine infusion undergoing cesarean section.

Detailed Description

Post-spinal anesthesia hypotension is a frequent complication during spinal anesthesia for cesarean section. The incidence of post-spinal anesthesia hypotension is as high as 62.1-89.7% if prophylacti...

Eligibility Criteria

Inclusion

  • 18-40 years
  • Primipara or multipara
  • Singleton pregnancy ≥37 weeks
  • American Society of Anesthesiologists physical status classification I to II
  • Scheduled for elective cesarean section under spinal anesthesia

Exclusion

  • Body height \< 150 cm
  • Body weight \> 100 kg or body mass index (BMI) ≥ 40 kg/m2
  • Eclampsia or chronic hypertension or baseline blood pressure ≥ 160mmHg
  • Hemoglobin \< 7g/dl
  • Fetal distress, or known fetal developmental anomaly

Key Trial Info

Start Date :

July 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 27 2021

Estimated Enrollment :

193 Patients enrolled

Trial Details

Trial ID

NCT04272580

Start Date

July 1 2020

End Date

March 27 2021

Last Update

July 6 2021

Active Locations (1)

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General Hospital of Ningxia Medical University

Yinchuan, Ningxia, China, 750004