Status:
UNKNOWN
EAS Familial Hypercholesterolaemia Studies Collaboration
Lead Sponsor:
Imperial College London
Conditions:
Familial Hypercholesterolemia
Eligibility:
All Genders
Brief Summary
Familial hypercholesterolaemia (FH) is a common genetic disorder resulting in marked elevations in low-density lipoprotein cholesterol (LDL-C). If untreated, lifelong exposure to elevated LDL-C result...
Detailed Description
Familial hypercholesterolaemia (FH) is a common genetic disorder affecting low-density lipoprotein cholesterol (LDL-C) metabolism, resulting in reduced catabolism of LDL particles and marked elevation...
Eligibility Criteria
Inclusion
- Clinical and/or genetic diagnosis of heterozygous or homozygous familial hypercholesterolaemia (FH)
- Relatives of index cases without a diagnosis of FH where screening (cascade or other) is carried out.
- The data have been de-identified prior to transferring to the EAS FHSC Global Registry.
Exclusion
- Secondary causes of dyslipidaemia (e.g. untreated hypothyroidism, cholestasis, nephrotic syndrome).
- Where data collection does not conform to the local or country wide standards for anonymised data.
Key Trial Info
Start Date :
March 22 2015
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
75000 Patients enrolled
Trial Details
Trial ID
NCT04272697
Start Date
March 22 2015
End Date
December 1 2025
Last Update
August 31 2021
Active Locations (1)
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1
School of Public Health, Imperial College London
London, United Kingdom, W6 8RP