Status:
COMPLETED
Potential Role of AGEs in Paediatric Allergies
Lead Sponsor:
Federico II University
Conditions:
Allergy
Eligibility:
All Genders
5-15 years
Brief Summary
Food allergy (FA) is "an adverse health effect arising from a specific immune response that occurs reproducibly" according to the 2010 National Institute of Allergy and Infectious Diseases, National I...
Detailed Description
The study is designed to evaluate the AGEs concentration in allergic children compared with healthy controls and to investigate the potential role of AGEs in FA pathogenesis. First, the investigators ...
Eligibility Criteria
Inclusion
- Caucasian ethnicity
- Both sexes
- Age ≥ 5 and ≤15 years with confirmed diagnosis of allergy (food and/or respiratory), and healthy controls age- and sex-matched.
Exclusion
- Non caucasian ethnicity
- Age \<5 or \>15 years
- Concomitant presence of other chronic diseases not related to allergy (i.e., malignancy, immunodeficiency, cystic fibrosis, celiac disease, autoimmune diseases, neuropsychiatric diseases, diabetes mellitus type 1, chronic inflammatory bowel diseases, malformations of the urinary tract, gastrointestinal tract and/or respiratory tract, genetic-metabolic disorders, nervous system diseases, delayed psychomotor development, chronic lung diseases, hematological diseases)
- Presence of tattoos, scars, moles or lesions on both forearms
Key Trial Info
Start Date :
January 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 30 2020
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04273152
Start Date
January 1 2018
End Date
March 30 2020
Last Update
October 11 2021
Active Locations (1)
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1
Pediatric Office
Naples, Italy, 80100