Status:
UNKNOWN
Effect of Three Types of Fluoride Varnish in Preventing Early Childhood Caries
Lead Sponsor:
The University of Hong Kong
Collaborating Sponsors:
Research Grants Council, Hong Kong
Conditions:
Early Childhood Caries
Eligibility:
All Genders
3-4 years
Phase:
NA
Brief Summary
This study evaluates and compares the effect of two types of calcium- and phosphate-containing fluoride varnishes to conventional fluoride varnishes in preventing early childhood caries.
Detailed Description
Fluoride vanish is the most commonly used professionally applied topical agent. Traditional fluoride vanish application has been reported to exhibit significant caries inhibiting effect in both perman...
Eligibility Criteria
Inclusion
- Generally healthy children age between 3-4 of age with unremarkable medical history and at high caries risk with at least one carious lesion (precavitated or cavitated) (Agouropoulos et al 2014). The high caries risk children are chosen because it is anticipated that they will benefit more from the topical fluoride varnish application than the low caries risk children.
Exclusion
- Patients who had received professional fluoride application in the past 6 months
- Patients with underlying medical history or special health care needs
- Patient who are uncooperative or refuse the treatment
- Patient who are allergic to milk protein (as MI VarnishTM contains "casein, a milk protein)
- Patient with contraindication for fluoride varnish e.g. hypersensitivity to colophony and/or any other constituents
- Patient who have primary teeth with enamel hypoplasia
Key Trial Info
Start Date :
March 13 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2022
Estimated Enrollment :
570 Patients enrolled
Trial Details
Trial ID
NCT04274569
Start Date
March 13 2019
End Date
October 1 2022
Last Update
February 18 2020
Active Locations (1)
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1
The University of Hong Kong
Hong Kong, Hong Kong, 999077