Status:

COMPLETED

Clinical Study of Anti-CD147 Humanized Meplazumab for Injection to Treat With 2019-nCoV Pneumonia

Lead Sponsor:

Tang-Du Hospital

Conditions:

Coronavirus Disease 2019 (COVID-19)

Eligibility:

All Genders

18-75 years

Phase:

PHASE1

PHASE2

Brief Summary

To evaluate the safety and efficacy of humanized Meplazumab for Injection in patients infected by 2019-nCoA.

Detailed Description

According to the results of nonclinical study of humanized Meplazumab for Injection, a single dose will be used for the treatment. The treatment plan is first dose on the first day (0d) and second dos...

Eligibility Criteria

Inclusion

  • Men and women aged 18 to 75 years (inclusive)
  • In line with the new coronavirus infection pneumonia diagnosis and treatment plan (trial version 4) issued by the Health Commission, patients with new coronavirus (2019 ncov) pneumonia were clinically diagnosed;
  • The subjects must be able to understand the study and willing to participate in the study, and sign the informed consent (if the subjects with no behavioral ability think it is in their own interests to participate in the test, they should sign the informed consent by their legal guardian, or notify the consent by phone (recording) and explain it in the original medical record and other relevant documents).

Exclusion

  • Known or expected to have allergic reactions or a history of allergy to any of the ingredients treated in this trial;
  • In the judgment of the investigator, there are other reasons that the patient is not suitable to participate in this study.

Key Trial Info

Start Date :

February 3 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 9 2020

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT04275245

Start Date

February 3 2020

End Date

March 9 2020

Last Update

April 9 2021

Active Locations (1)

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1

Tangdu Hospital

Xi'an, Shaanxi, China, 710032