Status:

COMPLETED

Pathological and Nuclear Medicine Factors for Prognosis in Lung Carcinoma

Lead Sponsor:

Klinikum Bayreuth GmbH

Collaborating Sponsors:

Peking University Cancer Hospital & Institute

Sana Klinikum Hof

Conditions:

NSCLC

Eligibility:

All Genders

18+ years

Brief Summary

Retrospective study in patients with therapy-naive non small cell lung carcinoma correlating presurgical F18-FDG-PET/CT imaging texture analysis data with postsurgical molecular pathology data and cli...

Detailed Description

Section 1:title and overview Title: Relationship between histopathological features, mutation status, 18F-FDG PET/CT radiomic imaging parameters as well as clinical outcome in patients with treatment-...

Eligibility Criteria

Inclusion

  • Retrospective selection of both German cohort NSCLC patients with concomitant gene mutation results, CTCs accounting results and 18F-FDG PET/CT imaging data before lung tumor surgery (both German patient cohorts)
  • Retrsopective selection of Chinese NSCLC patients with concomitant gene mutation results, CTCs accounting results and 18F-FDG PET/CT imaging data before lung tumor surgery (Chinese patient collective)

Exclusion

  • NSCLC patients with surgical resection of the target/primary tumor before 18F-FDG PET/CT scanning.
  • NSCLC patients with elevated blood glucose levels (\> 150 mg/dl) immediately before 18F-FDG injection.
  • based on PET CT scanning no concomitant malignancies

Key Trial Info

Start Date :

July 1 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2020

Estimated Enrollment :

2000 Patients enrolled

Trial Details

Trial ID

NCT04276025

Start Date

July 1 2016

End Date

January 1 2020

Last Update

February 19 2020

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