Status:

COMPLETED

Study of the Discriminating Power of a Blood Biomarker for Omega-3 Polyunsaturated Fatty Acid Content of the Retina for Age-related Macular Degeneration (AMD)

Lead Sponsor:

Centre Hospitalier Universitaire Dijon

Conditions:

Age-related Macular Degeneration

Eligibility:

All Genders

50+ years

Brief Summary

Age-related macular degeneration is a chronic degenerative retinal disease, which can lead to a progressive loss of visual acuity without affecting peripheral vision. It is a public health problem as ...

Eligibility Criteria

Inclusion

  • Subject who has provided written informed consent for participation in the study and genetic analyses
  • Subject aged 50 years or older
  • Subject with exudative AMD or
  • Subject with macular disorder requiring cataract surgery

Exclusion

  • Person not affiliated to the national health insurance system
  • Protected adults (curatorship, guardianship)
  • Persons deprived of their liberty by judicial or administrative decision
  • Adult unable to express consent
  • Subject who has already participated in the study
  • Subject with pre-existing maculopathy not labelled AMD
  • Subject refusing blood sample
  • Subject with diabetes
  • Subject on antibiotics or having had an antibiotic treatment in the last 3 months
  • Subject with a BMI \< 18.5 or \> 30 kg/m2
  • Subject with extreme eating habits (veganism, bulimia, anorexia)
  • Subject currently on a diet with avoidance of certain types of food or a low-calorie diet
  • Subject with an inflammatory disease (especially digestive disease)
  • Subject having undergone bariatric surgery
  • Subject having digestive tract malformations

Key Trial Info

Start Date :

February 11 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 9 2020

Estimated Enrollment :

205 Patients enrolled

Trial Details

Trial ID

NCT04278300

Start Date

February 11 2020

End Date

September 9 2020

Last Update

November 24 2020

Active Locations (1)

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1

CHU dijon Bourgogne

Dijon, France, 21079