Status:

COMPLETED

Testing Different Modes of Cognitive Behavior Therapy

Lead Sponsor:

Northwestern University

Conditions:

Depression

Literacy

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to test a novel behavioral treatment - Adapted Cognitive-Behavior Therapy (ACBT) - against standard Cognitive Behavior Therapy (CBT). The goal of the study is to determine...

Eligibility Criteria

Inclusion

  • 18 years of age or older
  • female
  • diagnosis of major depressive disorder (MDD) according to DSM-5 (Diagnostic and Statistical Manual-5) (and no specifiers that pertain to exclusionary criteria (e.g. MDD with psychotic features)
  • able and willing to give informed consent
  • able to communicate in English
  • willingness to be randomized to therapy
  • willing to complete all study assessments
  • at baseline, no plans to move from the Chicago area during the duration of the study

Exclusion

  • history of bipolar disorder
  • history of psychosis
  • current substance use disorder of moderate or severe level of severity
  • suicidal intentions or actions within the past three months
  • known neurologic disease (e.g., multiple sclerosis, Parkinson's disease, cerebrovascular accident) and/or cognitive or neurologic impairment (e.g., Alzheimer's disease)
  • current participation in other psychotherapy (not including psychiatric appointments pertaining to medication management)
  • inadequate vision or hearing to interact with study materials
  • being a prisoner, detainee, or being in police custody
  • any current involvement in litigation

Key Trial Info

Start Date :

February 14 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 15 2023

Estimated Enrollment :

22 Patients enrolled

Trial Details

Trial ID

NCT04279028

Start Date

February 14 2020

End Date

November 15 2023

Last Update

February 29 2024

Active Locations (1)

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1

James W. Griffith

Chicago, Illinois, United States, 60611