Status:

COMPLETED

Chimeric Antigen Receptor T-cell and Cellular Therapies for the Treatment of cAncer or BLood Diseases: Evaluation of Reporting of Adverse Events

Lead Sponsor:

Groupe Hospitalier Pitie-Salpetriere

Conditions:

Adverse Drug Reactions

Cancer

Eligibility:

All Genders

Up to 100 years

Brief Summary

CAR-T cells and cellular therapies may lead to various adverse reactions. This study investigates reports of different toxicities for cellular therapies in the World Health Organization's (WHO) global...

Detailed Description

CAR-T cells and cellular therapies are responsible of a wide range of side effects.The investigators use VigiBase, the World Health Organization (WHO) database of individual safety case reports, to id...

Eligibility Criteria

Inclusion

  • Case reported in the World Health Organization (WHO) database of individual safety case reports to 01/01/2020
  • Adverse events reported were including any MedDRA terms
  • Patients treated with cellular therapies reported in the WHO database.

Exclusion

  • Chronology not compatible between the drug and the toxicity

Key Trial Info

Start Date :

January 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 8 2023

Estimated Enrollment :

100000 Patients enrolled

Trial Details

Trial ID

NCT04279470

Start Date

January 1 2019

End Date

April 8 2023

Last Update

April 13 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hôpital Pitié-Salpêtrière

Paris, France, 75013