Status:
COMPLETED
Platelet PAR-1 Activation in Health and Diabetes
Lead Sponsor:
Vanderbilt University Medical Center
Conditions:
Type 2 Diabetes
Healthy
Eligibility:
All Genders
60+ years
Brief Summary
Platelet activation has been associated with bad events like heart attack and stroke. There are a variety of platelet activators that regulate how active a platelet is. We are interested in Protease-a...
Eligibility Criteria
Inclusion
- Healthy men and women ≥60 years of age OR
- Type 2 diabetic men and women ≥60 years of age
Exclusion
- Active cancer
- Prior myocardial infarction, prior stroke, diagnosed peripheral artery disease
- Severe liver (cirrhosis, cancer, or end-stage liver disease), kidney disease (eGFR \<30 cc/min).
- Pregnancy or lactation
- Active vasculitis
- Anticipated lifespan \< 2 years
- Current use of a DOAC
Key Trial Info
Start Date :
June 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 2 2021
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04280549
Start Date
June 1 2018
End Date
February 2 2021
Last Update
March 19 2025
Active Locations (1)
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1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232