Status:

COMPLETED

Point-of-care Monitoring of Antibiotic Concentration in Blood With UV-VIS Absorption Spectroscopy

Lead Sponsor:

Uppsala University

Conditions:

Sepsis

Infection, Bacterial

Eligibility:

All Genders

18+ years

Brief Summary

This prospective clinical study will investigate if antibiotic concentrations in patients with severe infections can be monitored by the UV-VIS spectroscopy.

Detailed Description

Early and correct antibiotic treatment has a fundamental effect on survival in severe infections, and to prevent resistance development. However, it is unclear if this is achieved in severely ill pati...

Eligibility Criteria

Inclusion

  • More than 18 years old
  • Suspected infection where treatment with cefotaxime, piperacillin/tazobactam or meropenem is prescribed

Exclusion

  • Pregnancy
  • Intermittent haemodialysis
  • Patient with limited treatment decision

Key Trial Info

Start Date :

August 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 10 2023

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT04282785

Start Date

August 1 2022

End Date

August 10 2023

Last Update

June 11 2025

Active Locations (1)

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1

Uppsala university hospital

Uppsala, Uppsala County, Sweden, 75185